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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736036
Species: Homo sapiens
RGD Object: Gene
Symbol: CTSL
Name: cathepsin L
Acc ID: CHEBI:61057
Term: tacrolimus hydrate
Definition: A hydrate that is the monohydrate form of tacrolimus.
Chemical ID: MESH:D016559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CTSLincreases expressionISOCtsl (Mus musculus)6480464CTDTacrolimus results in increased expression of CTSL mRNAPMID:25270620
CTSLincreases expressionISOCtsl (Rattus norvegicus)6480464CTDTacrolimus results in increased expression of CTSL mRNAPMID:21865292
CTSLmultiple interactionsISOCtsl (Mus musculus)6480464CTDTacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CTSL protein]PMID:18172886
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