GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CASP3 | increases cleavage | EXP | | 6480464 | CTD | Tacrolimus results in increased cleavage of CASP3 protein | PMID:35033536 | CASP3 | multiple interactions | EXP | | 6480464 | CTD | Tacrolimus inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein] | PMID:12871656 PMID:15548389 | CASP3 | increases activity | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Tacrolimus results in increased activity of CASP3 protein | PMID:15207740 | CASP3 | increases activity | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | Tacrolimus results in increased activity of CASP3 protein | PMID:17166486 PMID:17385075 PMID:24959755 | CASP3 | increases cleavage | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Tacrolimus results in increased cleavage of CASP3 protein | PMID:27606422 | CASP3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | Tacrolimus inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein] | PMID:10205001 | CASP3 | multiple interactions | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | MK0626 inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; NGF protein inhibits the reaction [Tacrolimus results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [3-nitropropionic acid results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein] | PMID:12642403 PMID:12892836 PMID:15571979 PMID:17385075 PMID:20149694 PMID:24959755 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |