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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2897
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il3
Name: interleukin 3
Acc ID: CHEBI:61057
Term: tacrolimus hydrate
Definition: A hydrate that is the monohydrate form of tacrolimus.
Chemical ID: MESH:D016559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il3decreases expressionISOIL3 (Homo sapiens)6480464CTDTacrolimus results in decreased expression of IL3 proteinPMID:11407316
Il3multiple interactionsISOIl3 (Mus musculus)6480464CTDSirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein]PMID:1376361
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