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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553810
Species: Mus musculus
RGD Object: Gene
Symbol: Bmp7
Name: bone morphogenetic protein 7
Acc ID: CHEBI:61057
Term: tacrolimus hydrate
Definition: A hydrate that is the monohydrate form of tacrolimus.
Chemical ID: MESH:D016559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:6207436480464CTDTacrolimus results in decreased expression of BMP7 protein

PMID:17703430
multiple interactionsISORGD:6207436480464CTDRamipril inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein], valsartan inhibits the reaction [Tacrolimus results in decreased expression of BMP7 protein]

PMID:17703430
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.