GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmox1 | increases expression | EXP | | 6480464 | CTD | Tacrolimus results in increased expression of HMOX1 mRNA; Tacrolimus results in increased expression of HMOX1 protein | PMID:23958496 | Hmox1 | decreases expression | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | Tacrolimus results in decreased expression of HMOX1 protein | PMID:24959755 | Hmox1 | increases expression | ISO | HMOX1 (Homo sapiens) | 6480464 | CTD | Tacrolimus results in increased expression of HMOX1 mRNA; Tacrolimus results in increased expression of HMOX1 protein | PMID:26260164 PMID:29362864 | Hmox1 | multiple interactions | ISO | Hmox1 (Rattus norvegicus) | 6480464 | CTD | MK0626 inhibits the reaction [Tacrolimus results in decreased expression of HMOX1 protein] | PMID:24959755 | |
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