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RGD ID: 3870
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlr4
Name: toll-like receptor 4
Acc ID: CHEBI:61048
Term: ganglioside GM1
Definition: A sialotetraosylceramide consisting of a branched pentasaccharide made up from one sialyl residue, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to N-stearoylsphingosine via a beta-linkage.
Chemical ID: MESH:D005677
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr4decreases expressionEXP 6480464CTDG(M1) Ganglioside results in decreased expression of TLR4 protein

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.