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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619930
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb11
Name: ATP binding cassette subfamily B member 11
Acc ID: CHEBI:6073
Term: Isradipine
Definition: null
Chemical ID: MESH:D017275
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb11decreases activityISORGD:7309446480464CTDIsradipine results in decreased activity of ABCB11 protein

PMID:24014644
Abcb11multiple interactionsISORGD:7309446480464CTDIsradipine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]

PMID:24014644
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.