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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344832
Species: Homo sapiens
RGD Object: Gene
Symbol: TNFSF10
Name: TNF superfamily member 10
Acc ID: CHEBI:6067
Term: isotretinoin
Definition: A retinoic acid that is all-trans-retinoic acid in which the double bond which is alpha,beta- to the carboxy group is isomerised to Z configuration. A synthetic retinoid, it is used for the treatment of severe cases of acne and other skin diseases.
Chemical ID: MESH:D015474
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFSF10increases expressionEXP 6480464CTDIsotretinoin results in increased expression of TNFSF10 mRNAPMID:18769122
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