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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731002
Species: Homo sapiens
RGD Object: Gene
Symbol: CASP3
Name: caspase 3
Acc ID: CHEBI:60579
Term: calcium oxalate
Definition: The calcium salt of oxalic acid, which in excess in the urine may lead to formation of oxalate calculi (kidney stones).
Chemical ID: MESH:D002129
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CASP3increases cleavageEXP 6480464CTDCalcium Oxalate results in increased cleavage of CASP3 proteinPMID:34333021
CASP3multiple interactionsEXP 6480464CTDSIRT1 protein inhibits the reaction [Calcium Oxalate results in increased cleavage of CASP3 protein]PMID:34333021
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