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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3870
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tlr4
Name: toll-like receptor 4
Acc ID: CHEBI:60484
Term: phosphatidylinositol dimannoside
Definition: A glycosylphosphatidylinositol having two D-mannosyl groups as the glycosyl moieties; obtained via extraction of the cell wall of Mycobacterium bovis.
Chemical ID: MESH:C054977
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr4multiple interactionsISORGD:7370146480464CTDTLR4 gene mutant form inhibits the reaction [[phosphatidylinositol dimannoside analog co-treated with Thioglycolates] results in increased expression of IL6 protein]

PMID:21936536
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