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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619571
Species: Mus musculus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:60312
Term: 2-amino-2-deoxy-D-galactopyranose
Definition: The pyranose form of D-galactosamine.
Chemical ID: MESH:D005688
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3multiple interactionsEXP 6480464CTD[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in decreased phosphorylation of MAPK3 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MAPK3 protein modified form; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK3 protein modified form; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK3 protein modified form]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MAPK3 protein modified form]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK3 protein modified form]PMID:20558151 PMID:20850421 PMID:28887131
Mapk3increases phosphorylationISOMapk3 (Rattus norvegicus)6480464CTDGalactosamine results in increased phosphorylation of MAPK3 proteinPMID:25620059
Mapk3multiple interactionsISOMapk3 (Rattus norvegicus)6480464CTDGenistein inhibits the reaction [Galactosamine results in increased phosphorylation of MAPK3 protein]PMID:25620059
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