GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | decreases expression | EXP | | 6480464 | CTD | Isoflurane results in decreased expression of NFE2L2 mRNA; Isoflurane results in decreased expression of NFE2L2 protein | PMID:36027947 | Nfe2l2 | decreases phosphorylation | EXP | | 6480464 | CTD | Isoflurane results in decreased phosphorylation of NFE2L2 protein | PMID:36027947 | Nfe2l2 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of NFE2L2 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 mRNA]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of NFE2L2 protein] | PMID:36027947 | Nfe2l2 | increases expression | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Isoflurane results in increased expression of NFE2L2 protein | PMID:32663520 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | NFE2L2 protein affects the reaction [trilobatin inhibits the reaction [Isoflurane results in decreased activity of CAT protein]]; trilobatin promotes the reaction [Isoflurane results in increased expression of NFE2L2 protein] | PMID:32663520 | | ||||||||||||||||||||||
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