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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308846
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Irak3
Name: interleukin-1 receptor-associated kinase 3
Acc ID: CHEBI:59524
Term: lipoarabinomannan
Definition: A glycolipid comprising a glycosylphosphatidyl-myo-inositol-anchored lipoglycan; a virulence factor associated with Mycobacterium tuberculosis.
Chemical ID: MESH:C050016
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Irak3increases expression ISORGD:131885436049804RGDLipoarabinomannan increases expression of Irak3 mRNA and protein in macrophages 
Irak3increases expressionISORGD:13188546480464CTDlipoarabinomannan results in increased expression of IRAK3 proteinPMID:16263713
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