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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736208
Species: Homo sapiens
RGD Object: Gene
Symbol: CEBPB
Name: CCAAT enhancer binding protein beta
Acc ID: CHEBI:59219
Term: ceruletide
Definition: A decapeptide comprising 5-oxoprolyl, glutamyl, aspartyl, O-sulfotyrosyl, threonyl, glycyl, tryptopyl, methionyl, aspartyl and phenylalaninamide residues in sequence. Found in the skins of certain Australian amphibians, it is an analogue of the gastrointestinal peptide hormone cholecystokinin and stimulates gastric, biliary, and pancreatic secretion. It is used in cases of paralysis of the intestine (paralytic ileus) and as a diagnostic aid in pancreatic malfunction.
Chemical ID: MESH:D002108
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CEBPBincreases expressionISOCebpb (Rattus norvegicus)6480464CTDCeruletide results in increased expression of CEBPB mRNAPMID:26873426
CEBPBmultiple interactionsISOCebpb (Rattus norvegicus)6480464CTD[Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPB protein; Dietary Fats promotes the reaction [Ceruletide results in increased expression of CEBPB mRNA]; Quercetin inhibits the reaction [[Dietary Fats co-treated with Ceruletide] results in increased expression of CEBPB protein]; Quercetin inhibits the reaction [Ceruletide results in increased expression of CEBPB mRNA]PMID:26873426
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