Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12328669
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: PTGS1
Name: prostaglandin-endoperoxide synthase 1
Acc ID: CHEBI:59033
Term: metamizole sodium
Definition: An organic sodium salt of antipyrine substituted at C-4 by a methyl(sulfonatomethyl)amino group, commonly used as a powerful analgesic and antipyretic.
Chemical ID: MESH:D004177
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS1decreases activityEXP 6480464CTDDipyrone results in decreased activity of PTGS1 protein alternative form

PMID:12242329
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.