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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2905
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcr1
Name: C-X-C motif chemokine receptor 1
Acc ID: CHEBI:59030
Term: oleandrin
Definition: A steroid saponin that consists of oleandrigenin having a 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl residue attached to the oxygen function at position 3.
Chemical ID: MESH:C021065
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcr1increases expressionISORGD:13531946480464CTDoleandrin results in increased expression of CXCR1 mRNA oleandrin results in increased expression of CXCR1 protein

PMID:24172227
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