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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71004
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smad9
Name: SMAD family member 9
Acc ID: CHEBI:5885
Term: imperatorin
Definition: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.
Chemical ID: MESH:C031534
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smad9increases phosphorylationISORGD:7335186480464CTDimperatorin results in increased phosphorylation of SMAD9 protein

PMID:17980360
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