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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737381
Species: Homo sapiens
RGD Object: Gene
Symbol: ADRA2A
Name: adrenoceptor alpha 2A
Acc ID: CHEBI:5862
Term: idazoxan
Definition: A benzodioxine that is 2,3-dihydro-1,4-benzodioxine in which one of the hydrogens at position 2 has been replaced by a 4,5-dihydro-1H-imidazol-2-yl group.
Chemical ID: MESH:D019329
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ADRA2Amultiple interactionsISOAdra2a (Rattus norvegicus)6480464CTD[Idazoxan binds to and results in decreased activity of ADRA2A protein] which results in decreased susceptibility to amitrazPMID:10582558
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