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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309340
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk11
Name: mitogen-activated protein kinase 11
Acc ID: CHEBI:5855
Term: ibuprofen
Definition: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group.
Chemical ID: MESH:D007052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk11multiple interactionsISOMAPK11 (Homo sapiens)6480464CTDMAPK11 protein promotes the reaction [Ibuprofen results in increased expression of NGFR protein]PMID:18056468
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