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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731324
Species: Homo sapiens
RGD Object: Gene
Symbol: ODC1
Name: ornithine decarboxylase 1
Acc ID: CHEBI:582124
Term: myriocin
Definition: An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.
Chemical ID: MESH:C001996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ODC1multiple interactionsEXP 6480464CTDthermozymocidin inhibits the reaction [resveratrol results in decreased activity of ODC1 protein]PMID:17521618
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