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RGD ID: 620665
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fasn
Name: fatty acid synthase
Acc ID: CHEBI:582124
Term: myriocin
Definition: An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.
Chemical ID: MESH:C001996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasnmultiple interactionsISORGD:16152006480464CTD[thermozymocidin results in increased susceptibility to Dexamethasone] which results in decreased expression of FASN mRNA

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