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RGD ID: 619831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:582124
Term: myriocin
Definition: An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.
Chemical ID: MESH:C001996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasmultiple interactionsISORGD:13462666480464CTDthermozymocidin inhibits the reaction [[sorafenib co-treated with vorinostat] affects the localization of and results in increased activity of FAS protein]

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