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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347691
Species: Homo sapiens
RGD Object: Gene
Symbol: FASN
Name: fatty acid synthase
Acc ID: CHEBI:582124
Term: myriocin
Definition: An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.
Chemical ID: MESH:C001996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FASNmultiple interactionsISOFasn (Mus musculus)6480464CTD[thermozymocidin results in increased susceptibility to Dexamethasone] which results in decreased expression of FASN mRNAPMID:31053639
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