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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70492
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nat2
Name: N-acetyltransferase 2
Acc ID: CHEBI:5775
Term: hydralazine
Definition: The 1-hydrazino derivative of phthalazine; a direct-acting vasodilator that is used as an antihypertensive agent.
Chemical ID: MESH:D006830
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nat2affects metabolic processingISONAT2 (Homo sapiens)6480464CTDNAT2 protein affects the metabolism of HydralazinePMID:15627487
Nat2increases acetylationISONAT2 (Homo sapiens)6480464CTDNAT2 protein results in increased acetylation of HydralazinePMID:15627487
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