Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3032
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smad3
Name: SMAD family member 3
Acc ID: CHEBI:5759
Term: Honokiol
Definition: A biphenyl that has formula C18H18O2.
Chemical ID: MESH:C005499
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smad3multiple interactionsEXP 6480464CTDhonokiol inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]PMID:21265825
Smad3multiple interactionsISOSMAD3 (Homo sapiens)6480464CTDhonokiol inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]PMID:32032644
Smad3multiple interactionsISOSmad3 (Mus musculus)6480464CTDhonokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]PMID:32032644
Go Back to source page   Continue to Ontology report