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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2326
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cebpa
Name: CCAAT/enhancer binding protein alpha
Acc ID: CHEBI:5674
Term: herbimycin
Definition: A 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. It is an ansamycin antibiotic that induces apoptosis and displays antitumour effects.
Chemical ID: MESH:C020754
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDherbimycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [[CEBPA protein binds to CEBPB protein] which binds to PTGS2 promoter]]

PMID:11133817
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