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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736022
Species: Mus musculus
RGD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: CHEBI:566274
Term: malonaldehyde
Definition: A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.
Chemical ID: MESH:D008315
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appincreases abundanceEXP 6480464CTDAPP protein modified form results in increased abundance of MalondialdehydePMID:29545167
Appmultiple interactionsEXP 6480464CTDvitexin inhibits the reaction [APP protein modified form results in increased abundance of Malondialdehyde]PMID:29545167
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