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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708525
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fndc5
Name: fibronectin type III domain containing 5
Acc ID: CHEBI:566274
Term: malonaldehyde
Definition: A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.
Chemical ID: MESH:D008315
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fndc5decreases abundanceEXP 6480464CTDFNDC5 protein results in decreased abundance of MalondialdehydePMID:32165127
Fndc5multiple interactionsEXP 6480464CTDNFE2L2 protein promotes the reaction [FNDC5 protein results in decreased abundance of Malondialdehyde]PMID:32165127
Fndc5multiple interactionsISOFndc5 (Mus musculus)6480464CTDFNDC5 protein inhibits the reaction [AGT protein modified form results in increased abundance of Malondialdehyde]PMID:30703374
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