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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730901
Species: Homo sapiens
RGD Object: Gene
Symbol: HMOX1
Name: heme oxygenase 1
Acc ID: CHEBI:5615
Term: halothane
Definition: A haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position.
Chemical ID: MESH:D006221
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMOX1increases expressionISOHmox1 (Mus musculus)6480464CTDHalothane results in increased expression of HMOX1 mRNAPMID:32795494
HMOX1multiple interactionsISOHmox1 (Mus musculus)6480464CTD[Ryanodine co-treated with Halothane] results in increased expression of HMOX1 mRNA; Dantrolene inhibits the reaction [Halothane results in increased expression of HMOX1 mRNA]PMID:32795494
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