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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730830
Species: Homo sapiens
RGD Object: Gene
Symbol: NPY
Name: neuropeptide Y
Acc ID: CHEBI:5557
Term: guanethidine
Definition: A member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group.
Chemical ID: MESH:D006145
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NPYdecreases secretionEXP 6480464CTDGuanethidine results in decreased secretion of NPY proteinPMID:15003356
NPYdecreases expressionISONpy (Rattus norvegicus)6480464CTDGuanethidine results in decreased expression of NPY proteinPMID:14527964 PMID:9460767
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