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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:55365
Term: alpha-hexylcinnamaldehyde
Definition: A member of the class of cinnamaldehydes carrying a hexyl substituent at the alpha-position.
Chemical ID: MESH:C080043
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4affects expressionISOIl4 (Mus musculus)6480464CTDhexyl cinnamic aldehyde affects the expression of IL4 mRNAPMID:22302311
Il4multiple interactionsISOIL4 (Homo sapiens)6480464CTD[hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [hexyl cinnamic aldehyde co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 proteinPMID:31958493
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