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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305542
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fbl
Name: fibrillarin
Acc ID: CHEBI:5516
Term: sodium aurothiomalate
Definition: A variable mixture of the mono- and di-sodium salts of aurothiomalic acid. It is used for treatment of rheumatoid arthritis.
Chemical ID: MESH:D006052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fblaffects localizationISORGD:13136286480464CTDGold Sodium Thiomalate affects the localization of FBL protein

PMID:10942594
Fbldecreases activityISORGD:13136296480464CTDGold Sodium Thiomalate results in decreased activity of FBL protein

PMID:19077085
Fblmultiple interactionsISORGD:13136296480464CTDCD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein] IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein] IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein] IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]

PMID:19077085
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