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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619570
Species: Homo sapiens
RGD Object: Gene
Symbol: MAPK3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:5385
Term: gliotoxin
Definition: A pyrazinoindole with a disulfide bridge spanning a dioxo-substituted pyrazine ring; mycotoxin produced by several species of fungi.
Chemical ID: MESH:D005912
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPK3multiple interactionsISOMapk3 (Rattus norvegicus)6480464CTDGliotoxin results in increased phosphorylation of and results in increased activity of MAPK3 proteinPMID:17466404
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