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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61996
Species: Rattus norvegicus
RGD Object: Gene
Symbol: F2
Name: coagulation factor II, thrombin
Acc ID: CHEBI:53691
Term: amidotrizoic acid
Definition: A member of the class of benzoic acids that is benzoic acid having iodo substituents at the 2-, 4- and 6-positions and acetamido substituents at the 3- and 5-positions. It is used, mainly as its N-methylglucamine and sodium salts, as an X-ray contrast medium in gastrointestinal studies, angiography, and urography.
Chemical ID: MESH:D003973
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F2multiple interactionsISOF2 (Homo sapiens)6480464CTDDiatrizoate inhibits the reaction [F2 protein binds to SERPINC1 protein]PMID:2020943
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