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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agt
Name: angiotensinogen
Acc ID: CHEBI:5354
Term: Ginkgoic acid
Definition: A hydroxybenzoic acid that has formula C22H34O3.
Chemical ID: MESH:C112485
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtmultiple interactionsISOAgt (Mus musculus)6480464CTDginkgolic acid inhibits the reaction [AGT protein modified form results in increased expression of ACTA2 protein]; ginkgolic acid inhibits the reaction [AGT protein modified form results in increased expression of and affects the localization of PIN1 protein]; ginkgolic acid inhibits the reaction [AGT protein modified form results in increased expression of SUMO1 protein]; ginkgolic acid inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 mRNA]; ginkgolic acid inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein]; ginkgolic acid inhibits the reaction [AGT protein modified form results in increased sumoylation of PML protein]; ginkgolic acid inhibits the reaction [PML protein promotes the reaction [AGT protein modified form results in increased expression of PIN1 protein]]; ginkgolic acid inhibits the reaction [PML protein promotes the reaction [AGT protein modified form results in increased expression of TGFB1 protein]]; PML protein inhibits the reaction [ginkgolic acid inhibits the reaction [AGT protein modified form results in increased expression of PIN1 protein]]; PML protein inhibits the reaction [ginkgolic acid inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein]]PMID:29524504
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