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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1593282
Species: Rattus norvegicus
RGD Object: Gene
Symbol: RT1-Db1
Name: RT1 class II, locus Db1
Acc ID: CHEBI:53473
Term: beryllium sulfate
Definition: A metal sulfate in which the metal is beryllium (in the +2 oxidation state) and the ratio of beryllium to sulfate is 1:1.
Chemical ID: MESH:C020711
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RT1-Db1increases expressionISORGD:13498236480464CTDberyllium sulfate results in increased expression of HLA-DRB1 mRNAPMID:16314022
RT1-Db1increases response to substanceISORGD:13498236480464CTDHLA-DRB1 protein mutant form results in increased susceptibility to beryllium sulfatePMID:16272364
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