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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2632
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fshr
Name: follicle stimulating hormone receptor
Acc ID: CHEBI:53444
Term: potassium dichromate
Definition: A potassium salt that is the dipotassium salt of dichromic acid.
Chemical ID: MESH:D011192
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fshrdecreases expressionEXP 6480464CTDPotassium Dichromate results in decreased expression of FSHR mRNA; Potassium Dichromate results in decreased expression of FSHR proteinPMID:23470461 PMID:28192182
Fshrmultiple interactionsEXP 6480464CTD[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of FSHR protein; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR protein]PMID:23470461 PMID:33675932
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