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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11329
Species: Mus musculus
RGD Object: Gene
Symbol: Sod1
Name: superoxide dismutase 1, soluble
Acc ID: CHEBI:53444
Term: potassium dichromate
Definition: A potassium salt that is the dipotassium salt of dichromic acid.
Chemical ID: MESH:D011192
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod1decreases activityISOSod1 (Rattus norvegicus)6480464CTDPotassium Dichromate results in decreased activity of SOD1 proteinPMID:17822687
Sod1decreases activityISOSOD1 (Homo sapiens)6480464CTDPotassium Dichromate results in decreased activity of SOD1 proteinPMID:21681464
Sod1decreases expressionISOSod1 (Rattus norvegicus)6480464CTDPotassium Dichromate results in decreased expression of SOD1 mRNAPMID:23470461
Sod1increases activityISOSOD1 (Homo sapiens)6480464CTDPotassium Dichromate results in increased activity of SOD1 proteinPMID:29665407
Sod1increases expressionISOSOD1 (Homo sapiens)6480464CTDPotassium Dichromate results in increased expression of SOD1 mRNAPMID:11678601 PMID:18332044
Sod1multiple interactionsISOSod1 (Rattus norvegicus)6480464CTDAscorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of SOD1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of SOD1 mRNA]PMID:17822687 PMID:23470461
Sod1multiple interactionsISOSOD1 (Homo sapiens)6480464CTDprotocatechualdehyde inhibits the reaction [Potassium Dichromate results in increased activity of SOD1 protein]PMID:29665407
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