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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10802
Species: Mus musculus
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: CHEBI:534
Term: 1,4-bis(2-ethylhexyl) sulfosuccinate
Definition: A succinate ester that has formula C20H38O7S.
Chemical ID: MESH:D004143
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6decreases methylationEXP 6480464CTDDioctyl Sulfosuccinic Acid results in decreased methylation of IL6 promoterPMID:30728429
Il6multiple interactionsEXP 6480464CTDDioctyl Sulfosuccinic Acid results in increased expression of and results in increased secretion of IL6 proteinPMID:30728429
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