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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nqo2
Name: N-ribosyldihydronicotinamide:quinone reductase 2
Acc ID: CHEBI:53233
Term: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
Definition: The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium.
Chemical ID: MESH:C022616
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nqo2increases reductionISORGD:13516296480464CTDNQO2 protein results in increased reduction of thiazolyl blue

PMID:29281794
Nqo2multiple interactionsISORGD:13516296480464CTDresveratrol inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue], Tacrine inhibits the reaction [NQO2 protein results in increased reduction of thiazolyl blue]

PMID:29281794
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.