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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2085
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alb
Name: albumin
Acc ID: CHEBI:53218
Term: diphenylmethane-4,4'-diisocyanate
Definition: A diisocyanate consisting of diphenylmethane with two isocyanate groups at the 4- and 4'-positions.
Chemical ID: MESH:C005969
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Albaffects bindingEXP 6480464CTD4,4'-diphenylmethane diisocyanate binds to ALB proteinPMID:19928878
Albmultiple interactionsEXP 6480464CTD[4,4'-diphenylmethane diisocyanate binds to ALB protein] which results in increased chemical synthesis of N6-(((4-(4-(acetylamino)benzyl)phenyl)amino)carbonyl)lysine; [4,4'-diphenylmethane diisocyanate binds to ALB protein] which results in increased chemical synthesis of N6-(((4-(4-aminobenzyl)phenyl)amino)carbonyl)lysinePMID:19928878
Albmultiple interactionsISOALB (Homo sapiens)6480464CTD[4,4'-diphenylmethane diisocyanate co-treated with Glutathione] binds to and results in increased metabolism of ALB proteinPMID:23791970
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