GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CASP3 | increases expression | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form | PMID:24831514 PMID:26165751 PMID:30503585 | CASP3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of CASP3 protein]; Trinitrobenzenesulfonic Acid results in increased cleavage of and results in increased activity of CASP3 protein | PMID:22427801 | CASP3 | multiple interactions | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | dapagliflozin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; geraniol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Mesalamine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 protein modified form]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein]; Telmisartan inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CASP3 mRNA]; Trinitrobenzenesulfonic Acid results in increased activity of and results in increased cleavage of CASP3 protein; Trinitrobenzenesulfonic Acid results in increased expression of and results in increased activity of CASP3 protein | PMID:24831514 PMID:26165751 PMID:30503585 PMID:33412153 | | ||||||||||||||||||||||
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