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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3123
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Muc2
Name: mucin 2, oligomeric mucus/gel-forming
Acc ID: CHEBI:53063
Term: 2,4,6-trinitrobenzenesulfonic acid
Definition: The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.
Chemical ID: MESH:D014302
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Muc2decreases expressionEXP 6480464CTDTrinitrobenzenesulfonic Acid results in decreased expression of MUC2 mRNAPMID:19998380
Muc2increases expressionEXP 6480464CTDTrinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNAPMID:17449585
Muc2multiple interactionsEXP 6480464CTDActive Hexose Correlated Compound inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]; Sulfasalazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MUC2 mRNA]PMID:17449585
Muc2decreases expressionISOMuc2 (Mus musculus)6480464CTDTrinitrobenzenesulfonic Acid results in decreased expression of MUC2 mRNAPMID:25307695
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