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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318014
Species: Homo sapiens
RGD Object: Gene
Symbol: NLRP3
Name: NLR family pyrin domain containing 3
Acc ID: CHEBI:53063
Term: 2,4,6-trinitrobenzenesulfonic acid
Definition: The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.
Chemical ID: MESH:D014302
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NLRP3increases expressionISONlrp3 (Rattus norvegicus)6480464CTDTrinitrobenzenesulfonic Acid results in increased expression of NLRP3 proteinPMID:30365937
NLRP3multiple interactionsISONlrp3 (Rattus norvegicus)6480464CTDbergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NLRP3 protein]PMID:30365937
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