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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303089
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsn
Name: gelsolin
Acc ID: CHEBI:53063
Term: 2,4,6-trinitrobenzenesulfonic acid
Definition: The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.
Chemical ID: MESH:D014302
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:15506606480464CTDTrinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA

PMID:17982090, PMID:18200517
multiple interactionsISORGD:15506606480464CTDCurcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of GSN mRNA]

PMID:18200517
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.