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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352024
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL10
Name: C-X-C motif chemokine ligand 10
Acc ID: CHEBI:53049
Term: 1-fluoro-2,4-dinitrobenzene
Definition: The organofluorine compound that is benzene with a fluoro substituent at the 1-position and two nitro substituents in the 2- and 4-positions.
Chemical ID: MESH:D004139
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL10decreases expressionISOCxcl10 (Mus musculus)6480464CTDDinitrofluorobenzene results in decreased expression of CXCL10 mRNAPMID:23445166
CXCL10increases expressionISOCxcl10 (Mus musculus)6480464CTDDinitrofluorobenzene results in increased expression of CXCL10 mRNA; Dinitrofluorobenzene results in increased expression of CXCL10 proteinPMID:15719370
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