GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IFNG | affects expression | EXP | | 6480464 | CTD | nickel sulfate affects the expression of IFNG mRNA | PMID:11145678 | IFNG | increases secretion | EXP | | 6480464 | CTD | nickel sulfate results in increased secretion of IFNG protein | PMID:10929769 PMID:14650623 PMID:15270870 PMID:15663561 | IFNG | multiple interactions | EXP | | 6480464 | CTD | [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Cholecalciferol inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Dimethyl Fumarate inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; Hydrocortisone inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein]; IFNG protein promotes the reaction [nickel sulfate results in increased expression of IL27 mRNA]; Zinc Sulfate inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein] | PMID:14650623 PMID:15663561 PMID:29594315 PMID:30421605 | IFNG | increases expression | ISO | Ifng (Mus musculus) | 6480464 | CTD | nickel sulfate results in increased expression of IFNG mRNA | PMID:16166746 | |
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