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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736049
Species: Homo sapiens
RGD Object: Gene
Symbol: GPX4
Name: glutathione peroxidase 4
Acc ID: CHEBI:53001
Term: nickel sulfate
Definition: A metal sulfate having nickel(2+) as the metal ion.
Chemical ID: MESH:C029938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPX4increases expressionEXP 6480464CTDnickel sulfate results in increased expression of GPX4 mRNAPMID:18651567
GPX4multiple interactionsISOGpx4 (Rattus norvegicus)6480464CTD[nickel sulfate results in increased abundance of Nickel] which results in decreased expression of GPX4 mRNAPMID:31734292
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