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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1624041
Species: Mus musculus
RGD Object: Gene
Symbol: Fbxw7
Name: F-box and WD-40 domain protein 7
Acc ID: CHEBI:53001
Term: nickel sulfate
Definition: A metal sulfate having nickel(2+) as the metal ion.
Chemical ID: MESH:C029938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fbxw7multiple interactionsISOFBXW7 (Homo sapiens)6480464CTDFBXW7 mRNA affects the reaction [nickel sulfate results in increased degradation of MYC protein]; FBXW7 protein affects the reaction [nickel sulfate results in increased degradation of MYC protein]PMID:20046830
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