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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737005
Species: Homo sapiens
RGD Object: Gene
Symbol: GPX1
Name: glutathione peroxidase 1
Acc ID: CHEBI:52492
Term: mancozeb
Definition: A mixture composed from maneb and zineb, which is used as a broad-spectrum contact fungicide.
Chemical ID: MESH:C013099
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPX1decreases expressionISOGpx1 (Mus musculus)6480464CTDmancozeb results in decreased expression of GPX1 mRNAPMID:30037311
GPX1multiple interactionsISOGpx1 (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [mancozeb results in decreased expression of GPX1 mRNA]PMID:30037311
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